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A 2017 Cochrane review found limited but directionally positive evidence for magnesium supplementation in the treatment of nocturnal leg cramps 15
In addition to the physiological functions of protein-bound lipoic acid, there is increasing scientific and medical interest in potential therapeutic uses of pharmacological doses of free (unbound) lipoic acid (3)
Caution is needed with insulin or sulfonylureas, as hypoglycemia risk increases
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Turton MD, OShea D, Gunn I et al (1996) A role for glucagon-like peptide-1 in the central regulation of feeding
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